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Consciousness, Mechanisms Underlying Outcomes, and Ethical Considerations

383

77.Giacino JT, Kalmar K. Diagnostic and prognostic guidelines for the vegetative and minimally conscious states. Neuropsychol Rehabil 15, 166–174, 2005.

78.Strauss DJ, Ashwal S, Day SM, et al. Life expectancy of children in vegetative and minimally conscious states. Pediatr Neurol 23, 312–319, 2000.

79.Lammi MH, Smith VH, Tate RL, et al. The minimally conscious state and recovery potential: a follow-up study 2 to 5 years after traumatic brain injury. Arch Phys Med Rehabil 86, 746–754, 2005.

80.Cairns H, Oldfield RC, Pennybacker JB, et al. Akinetic mutism with an epidermoid cyst of the 3rd ventricle. Brain 84, 272–290, 1941.

81.Otto A, Zerr I, Lantsch M, et al. Akinetic mutism as a classification criterion for the diagnosis of Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry 64, 524–528, 1998.

82.Nemeth G, Hegedus K, Molnar L. Akinetic mutism associated with bicingular lesions: clinicopathological and functional anatomical correlates. Eur Arch Psychiatry Neurol Sci 237, 218–222, 1988.

83.Castaigne P, Buge A, Cambier J, et al. Thalamic dementia of vascular origin due to bilateral softening limited to the region of the retromamillary peduncle. Apropos of 2 anatomo-clinical cases. Rev Neurol (Paris) 89–107, 1966.

84.Segarra JM. Cerebral vascular disease and behavior. I. The syndrome of the mesencephalic artery (basilar artery bifurcation). Arch Neurol 22, 408–418, 1970.

85.Katz DI, Alexander MP, Mandell AM. Dementia following strokes in the mesencephalon and diencephalon. Arch Neurol 44, 1127–1133, 1987.

86.Fisher CM. Honored guest presentation: abulia minor vs. agitated behavior. Clin Neurosurg 31, 9–31, 1983.

87.Mega MS, Cohenour RC. Akinetic mutism: disconnection of frontal-subcortical circuits. Neuropsychiatry Neuropsychol Behav Neurol 10, 254–259, 1997.

88.Fleet WS, Valenstein E, Watson RT, et al. Dopamine agonist therapy for neglect in humans. Neurology 37, 1765–1770, 1987.

89.Stuss DT, Guberman A, Nelson R, et al. The neuropsychology of paramedian thalamic infarction. Brain Cogn 8, 348–378, 1988.

90.van Domburg PH, Ten Donkelaar HJ, Notermans SL. Akinetic mutism with bithalamic infarction. Neurophysiological correlates. J Neurol Sci 139, 58–65, 1996.

91.Burruss JW, Chacko RC. Episodically remitting akinetic mutism following subarachnoid hemorrhage. J Neuropsychiatry Clin Neurosci 11, 100–102, 1999.

92.Bernat JL. Questions remaining about the minimally conscious state. Neurology 58, 337–338, 2002.

93.Onofrj M, Thomas A, Paci C, et al. Event related potentials recorded in patients with locked-in syndrome. J Neurol Neurosurg Psychiatry 63, 759–764, 1997.

94.Leon-Carrion J, Van Eeckhout P, DominguezMorales MDR. Review of subject: the locked-in syndrome: a syndrome looking for a therapy. Brain Inj 16, 555–569, 2002.

95.Doble JE, Haig AJ, Anderson C, et al. Impairment, activity, participation, life satisfaction, and survival in persons with locked-in syndrome for over a decade: follow-up on a previously reported cohort. J Head Trauma Rehabil 18, 435–444, 2003.

96.Bauby J-D. The Diving Bell and the Butterfly. New York: Vintage International, 1997.

97.Ware JE, Snow KK, Kosinski M. SF-36 Health Survey Manual and Interpretation Guide. 1993.

98.Laureys S, Pellas F, Van Eeckhout P, et al. The locked-in syndrome: what is it like to be conscious but paralyzed and voiceless? Prog Brain Res 150, 495–511, 2005.

99.Laureys S, Owen AM, Schiff ND. Brain function in coma, vegetative state, and related disorders. Lancet Neurol 3, 537–546, 2004.

100.Levy DE, Sidtis JJ, Rottenberg DA, et al. Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients. Ann Neurol 22, 673– 682, 1987.

101.DeVolder AG, Goffinet AM, Bol A, et al. Brain glucose metabolism in postanoxic syndrome. Positron emission tomographic study. Arch Neurol 47, 197–204, 1990.

102.Tommasino C, Grana C, Lucignani G, et al. Regional cerebral metabolism of glucose in comatose and vegetative state patients. J Neurosurg Anesthesiol 7, 109– 116, 1995.

103.Rudolf J, Ghaemi M, Ghaemi M, et al. Cerebral glucose metabolism in acute and persistent vegetative state. J Neurosurg Anesthesiol 11, 17–24, 1999.

104.Laureys S, Faymonville ME, Degueldre C, et al. Auditory processing in the vegetative state. Brain 123, 1589–1601, 2000.

105.Schiff ND, Ribary U, Moreno DR, et al. Residual cerebral activity and behavioural fragments can remain in the persistently vegetative brain. Brain 125, 1210– 1234, 2002.

106.Blacklock JB, Oldfield EH, Di CG, et al. Effect of barbiturate coma on glucose utilization in normal brain versus gliomas. Positron emission tomography studies. J Neurosurg 67, 71–75, 1987.

107.Alkire MT, Miller J. General anesthesia and the neural correlates of consciousness. Prog Brain Res 150, 229–244, 2005.

108.Maquet P, Degueldre C, Delfiore G, et al. Functional neuroanatomy of human slow wave sleep. J Neurosci 17, 2807–2812, 1997.

109.Laureys S, Faymonville ME, Peigneux P, et al. Cortical processing of noxious somatosensory stimuli in the persistent vegetative state. Neuroimage 17, 732– 741, 2002.

110.Plum F, Schiff N, Ribary U, et al. Coordinated expression in chronically unconscious persons. Philos Trans R Soc Lond B Biol Sci 353, 1929–1933, 1998.

111.Schiff ND, Plum F. Cortical function in the persistent vegetative state. Trends Cogn Sci 3, 43–44, 1999.

112.Castaigne P, Lhermitte F, Buge A, et al. Paramedian thalamic and midbrain infarct: clinical and neuropathological study. Ann Neurol 10, 127–148, 1981.

113.Plum, F. Coma and related global disturbances of the human conscious state. In: Jones, E and Peters, P, eds. Cerebral Cortex, Vol. 9, Plenum Press, pp 359– 425, 1991.

114.Menon DK, Owen AM, Williams EJ, et al. Cortical processing in persistent vegetative state. Wolfson Brain Imaging Centre Team. Lancet 352, 1148–1149, 1998.

115.Macniven JA, Poz R, Bainbridge K, et al. Emotional adjustment following cognitive recovery from ‘persistent vegetative state’: psychological and personal perspectives. Brain Inj 17, 525–533, 2003.


384 Plum and Posner’s Diagnosis of Stupor and Coma

116.Menon DK, Owen AM, Pickard JD. Response from Menon, Owen and Pickard. Trends Cogn Sci 3, 44– 46, 1999.

117.Schiff N, Ribary U, Plum F, et al. Words without mind. J Cogn Neurosci 11, 650–656, 1999.

118.Zeki S. The visual association cortex. Curr Opin Neurobiol 3, 155–159, 1993.

119.Owen AM, Coleman MR, Menon DK, et al. Residual auditory function in persistent vegetative state: a combined PET and fMRI study. Neuropsychol Rehabil 15, 290–306, 2005.

120.Owen AM, Coleman MR, Boly M, et al. Detecting awareness in the vegetative state. Science 313, 1402, 2006.

121.Schiff ND, Rodriguez-Moreno D, Kamal A, et al. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 64, 514–523, 2005.

122.Boly M, Faymonville ME, Peigneux P, et al. Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state. Arch Neurol 61, 233–238, 2004.

123.Boly M, Faymonville ME, Peigneux P, et al. Cerebral processing of auditory and noxious stimuli in severely brain injured patients: differences between VS and MCS. Neuropsychol Rehabil 15, 283–289, 2005.

124.Wedekind C, Hesselmann V, Lippert-Gruner M, et al. Trauma to the pontomesencephalic brainstem- a major clue to the prognosis of severe traumatic brain injury. Br J Neurosurg 16, 256–260, 2002.

125.Bekinschtein T, Leiguarda R, Armony J, et al. Emo-

tion processing in the minimally conscious state. J Neurol Neurosurg Psychiatry 75, 788, 2004.

126.Rees G, Kreiman G, Koch C. Neural correlates of consciousness in humans. Nat Rev Neurosci 3, 261– 270, 2002.

127.Clauss RP, van der Merwe CE, Nel HW. Arousal from a semi-comatose state on zolpidem. S Afr Med J 91, 788–789, 2001.

128.Jennett B, Adams JH, Murray LS, et al. Neuropathology in vegetative and severely disabled patients after head injury. Neurology 56, 486–490, 2001.

129.Schiff ND, Plum F. The role of arousal and ‘‘gating’’ systems in the neurology of impaired consciousness. J Clin Neurophysiol 17, 438–452, 2000.

130.Plum F. Coma and related global disturbances of human consciousness. In: Jones E, Peters P, eds. Cerebral Cortex, Vol. 9. New York: Plenum Press, 1991.

131.Adams JH, Graham DI, Jennett B. The structural basis of moderate disability after traumatic brain damage. J Neurol Neurosurg Psychiatry 71, 521–524, 2001.

132.Voss HU, Ulug AM, Watts R, Heier LA, McCandliss B, Kobylarz E, Giacino, J, Ballon D, Schiff ND. Possible axonal regrowth in late recovery from minimally conscious state. Journal of Clinical Investigation 116, 2005–2011, 2006.

133.Dancause N, Barbay S, Frost SB, et al. Extensive cortical rewiring after brain injury. J Neurosci 25, 10167–10179, 2005.

134.Chklovskii DB, Mel BW, Svoboda K Cortical rewiring and information storage. Nature 431, 782–788, 2004.

135.Bengtsson SL, Nagy Z, Skare S, et al. Extensive piano practicing has regionally specific effects on white matter development. Nat Neurosci 8, 1148–1150, 2005.

136.Raichle ME, MacLeod AM, Snyder AZ, et al. A default mode of brain function. Proc Natl Acad Sci U S A 98, 676–682, 2001.

137.Gusnard DA, Raichle ME, Raichle ME. Searching for a baseline: functional imaging and the resting human brain. Nat Rev Neurosci 2, 685–694, 2001.

138.Gusnard DA, Akbudak E, Shulman GL, et al. Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci U S A 98, 4259–4264, 2001.

139.Greicius MD, Krasnow B, Reiss AL, et al. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A 100, 253–258, 2003.

140.Simpson JR Jr, Snyder AZ, Gusnard DA, et al. Emotion-induced changes in human medial prefrontal cortex: I. During cognitive task performance. Proc Natl Acad Sci U S A 98, 683–687, 2001.

141.Laureys S, Faymonville ME, Ferring M, et al. Differences in brain metabolism between patients in coma, vegetative state, minimally conscious state and lockedin syndrome. Eur J Neurol 10, 224–224, 2003.

142.Smith AJ, Blumenfeld H, Behar KL, et al. Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI. Proc Natl Acad Sci U S A 99, 10765–10770, 2002.

143.Logothetis NK, Pauls J, Augath M, et al. Neurophysiological investigation of the basis of the fMRI signal. Nature 412, 150–157, 2001.

144.Schiff ND, Purpura KP. Toward a neurophysiological basis for cognitive neuromodulation. Thalamus Rel Syst 2, 55–69, 2002.

145.Groenewegen HJ, Berendse HW. The specificity of the ‘nonspecific’ midline and intralaminar thalamic nuclei. Trends Neurosci 17, 52–57, 1994.

146.Van der Werf YD, Witter MP, Groenewegen HJ. The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness. Brain Res Brain Res Rev 39, 107–140, 2002.

147.Nguyen DK, Botez MI. Diaschisis and neurobehavior. Can J Neurol Sci 25, 5–12, 1998.

148.Gold L, Lauritzen M. Neuronal deactivation explains decreased cerebellar blood flow in response to focal cerebral ischemia or suppressed neocortical function. Proc Natl Acad Sci U S A 99, 7699–7704, 2002.

149.Timofeev I, Grenier F, Steriade M. Disfacilitation and active inhibition in the neocortex during the natural sleep-wake cycle: an intracellular study. Proc Natl Acad Sci U S A 98, 1924–1929, 2001.

150.McCormick DA, Shu Y, Hasenstaub A, et al. Persistent cortical activity: mechanisms of generation and effects on neuronal excitability. Cereb Cortex 13, 1219–1231, 2003.

151.Kasanetz F, Riquelme LA, Murer MG. Disruption of the two-state membrane potential of striatal neurones during cortical desynchronisation in anaesthetised rats. J Physiol 543, 577–589, 2002.

152.Robinson PA, Rennie CJ, Rowe DL. Dynamics of large-scale brain activity in normal arousal states and epileptic seizures. Phys Rev E Stat Nonlin Soft Matter Phys 65, 041924, 2002.

153.Santhakumar V, Ratzliff AD, Jeng J, et al. Long-term hyperexcitability in the hippocampus after experimental head trauma. Ann Neurol 50, 708–717, 2001.


Consciousness, Mechanisms Underlying Outcomes, and Ethical Considerations

385

154.Topolnik L, Steriade M, Timofeev I. Hyperexcitability of intact neurons underlies acute development of trauma-related electrographic seizures in cats in vivo. Eur J Neurosci 18, 486–496, 2003.

155.Williams D, Parsons-Smith G. Thalamic activity in stupor. Brain 74, 377–398, 1951.

156.Cohen L, Chaaban B, Habert MO. Transient improvement of aphasia with zolpidem. N Engl J Med 350, 949–950, 2004.

157.Szelies B, Herholz K, Pawlik G, et al. Widespread functional effects of discrete thalamic infarction. Arch Neurol 48, 178–182, 1991.

158.Caselli RJ, Graff-Radford NR, Rezai K. Thalamocortical diaschisis: single-photon emission tomographic study of cortical blood flow change after focal thalamic infarction. Neuropsychiatry Neuropsychol Behav Neurol 4, 193–214, 1991.

159.Ingvar DH. Reproduction of the 3 per second spike and wave EEG pattern by subcortical electrical stimulation in cats. Acta Physiol Scand 33, 137–150, 1955.

160.Kakigi R, Shibasaki H, Katafuchi Y, et al. The syndrome of bilateral paramedian thalamic infarction associated with an oculogyric crisis. Rinsho Shinkeigaku 26, 1100–1105, 1986.

161.Wilcox JA, Nasrallah HA. Organic factors in catatonia. Br J Psychiatry 149, 782–784, 1986.

162.Kamal AR, Schiff ND. Does the form of akinetic mutism linked to mesodiencephalic injuries bridge the double dissociation of Parkinson’s disease and catatonia? Behav Brain Sci 25, 586–587, 2002.

163.Berthier ML, Kulisevsky JJ, Gironell A, et al. Obsessive compulsive disorder and traumatic brain injury: behavioral,cognitive,andneuroimagingfindings.Neuropsychiatry Neuropsychol Behav Neurol 14, 23–31, 2001.

164.Sachs GA, Siegler M. Guidelines for decision making when the patient is incompetent. J Crit Illness 6, 348–359, 1991.

165.Terry PB, Vettese M, Song J, et al. End-of-life decision making: when patients and surrogates disagree. J Clin Ethics 10, 286–293, 1999.

166.Brock, DW. Patient Self-Determination Act. Trumping advance directives. Hastings Center Report 21, S5-S6, 1991.

167.Annas GJ. ‘‘Culture of life’’ politics at the bedside— the case of Terri Schiavo. N Engl J Med 352, 1710– 1715, 2005.

168.Hayward RS, Steinberg EP, Ford DE, et al. Preventive care guidelines: 1991. Ann Intern Med 114, 758– 783, 1991.

169.Wolf S, Barondess JA, Boyle P, et al. Special Report: Sources of concern about the Patient Self-Determina- tion Act. N Engl J Med 325, 1661–1671, 1991.

170.Fins JJ, Maltby BS, Friedman E, et al. Contracts, covenants and advance care planning: an empirical study of the moral obligations of patient and proxy. J Pain Symptom Manage 29, 55–86, 2005.

171.Fins JJ, Miller FG, Acres CA, et al. End-of-life decisionmaking in the hospital: current practices and future prospects. J Pain Symptom Manage 17, 6–15, 1999.

172.Bedell SE, Delbanco TL. Choices about the cardiopulmonary resuscitation in the hospital. When do physicians talk with patient? N Engl J Med 310, 1089–1093, 1984.

173.Fins JJ. Constructing an ethical stereotaxy for severe brain injury: balancing risks, benefits and access. Nature Rev Neurosci 4, 323–327, 2003.

174.Annas GJ. The ‘‘right to die’’ in America: Sloganeering from Quinlan and Cruzan to Quill and Kevorkian. Duquesne Law Review 34, 875–897, 1996.

175.Cantor NL. Twenty-five years after Quinlan: a review of the jurisprudence of death and dying. J Law Med Ethics 29, 182–196, 2001.

176.Cranford RE. Medical futility: transforming a clinical concept into legal and social policies. J Am Geriatr Soc 42, 894–898, 1994.

177.Fins JJ. Clinical pragmatism and the care of brain damaged patients: toward a palliative neuroethics for disorders of consciousness. Prog Brain Res 150, 565– 582, 2005.

178.Siminoff LA, Mercer MB, Arnold R. Families’ understanding of brain death. Prog Transplant 13, 218– 24, 2003.

179.Kimura R. Japan’s dilemma with the definition of death. Kennedy Inst Ethics J 1, 123–131, 1991.

180.Gutierrez E. Japan’s House of Representatives passes brain-death bill. Lancet 349, 1304, 1997.

181.Fins JJ. Across the divide: religious objections to brain death. J Religion Health 34, 33–39, 1995.

182.Jennett B, Plum F. Persistent vegetative state after brain damage. A syndrome in search of a name. Lancet 1, 734–737, 1972.

183.Kobylarz E, Schiff ND. Functional Imaging of severely brain-injured patients—progress, challenges, and limitations. Arch Neurol 61, 1357–1360, 2004.

184.Giacino J, Whyte J. The vegetative and minimally conscious states: current knowledge and remaining questions. J Head Trauma Rehabil 20, 30–50, 2005.

185.Fins JJ. A Palliative Ethic of Care: Clinical Wisdom at Life’s End. Sudbury, Mass.: Jones and Bartlett, 2006.

186.Fins JJ. Rethinking disorders of consciousness: new research and its implications. The Hastings Cancer Rep 35, 22–24, 2005.

187.Fins JJ. Affirming the right to care, preserving the

right to die: disorders of consciousness and neuroethics after Schiavo. Palliat Support Care 4, 169–178, 2006.

187a. Winslade, W. Confronting Traumatic Brain Injury. New Haven, Conn.: Yale University Press, 1998.

188.Sherer M, Hart T, Nick TG, et al. Early impaired self-awareness after traumatic brain injury. Arch Phys Med Rehabil 84, 168–176, 2003.

189.Farah MJ, Wolpe PR. Monitoring and manipulating brain function, new neuroscience technologies and their ethical implications. Hastings Center Report 34, 35–45, 2004.

190.Fins JJ. The Orwellian threat to emerging neurodiagnostic technologies. Am J Bioethics 5, 56–58, 2005.

191.Levine C. The loneliness of the long-term care giver. N Engl J Med 340, 1587–1590, 1999.

192.Kennedy PR, Bakay RAE. Restoration of neural output from a paralyzed patient by a direct brain connection. Neuro Report 9, 1707–1711, 1998.

193.Schiff ND. The neurology of impaired consciousness: challenges for cognitive neuroscience. In: Gazzaniga MS ed. The Cognitive Neurosciences, 3rd ed. Boston: MIT, 2004.

194.JoliotM,RibaryU,LlinasR.Humanoscillatorybrainactivity near 40 Hz coexists with cognitive temporal binding. Proc Natl Acad Sci USA 91, 11748–11751, 1994.



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Index

Page numbers followed by ‘‘t’’ denote tables; those followed by ‘‘b’’ denote boxes; and those followed by ‘‘f’’ denote figures

Abducens nerve anatomy of, 61 course of, 100 palsy of, 77, 113 paralysis of, 100

Abscess

brain, 141–142, 142f, 143t cerebellar, 149–150, 150t epidural, 126–127, 144 pontine, 170f

Abulia, 8

Accidental hypothermia, 259–260 Acetaminophen overdose, 245, 326 Acetic acid, 250

Acetylcholine, 208–209 Acid-base imbalances

acidosis. See Acidosis alkalosis. See Alkalosis hyperventilation and, 188–191 systemic, 258–259

treatment of, 315 Acidosis

lactic, 233, 250

metabolic. See Metabolic acidosis respiratory, 192, 192t

sodium bicarbonate for, 324, 326 Acute bacterial leptomeningitis, 262–265

Acute bacterial meningitis, 132–133, 133t, 263, 316f Acute cerebellar infarction, 139b

Acute disseminated encephalomyelitis description of, 157–158, 267f, 271–273 outcomes, 356, 367

Acute hemorrhagic leukoencephalopathy, 272 Acute hypoxia, 211–214

Acute liver failure, 224

Acute massive cerebral infarction, 138b Acute subdural hematoma, 123

Acute toxic encephalopathy, 266, 269–271 Addison’s disease, 235–236

Adenosine triphosphate, 198 Adrenal disorders, 234–236 Adrenoleukodystrophy, 278 Advance care planning, 376 Agitation, 6, 317

Airway

description of, 42–43 obstruction of, 211, 311

Akinetic mutism, 8, 360–362, 361b, 375 Alcohol

delirium tremens after withdrawal from, 283 intoxication caused by. See Ethanol intoxication

Alcoholic stupor, 242t, 243

Alcoholism, 246t Alkalosis

metabolic, 191t, 191–192, 231, 258 respiratory, 189–191, 190t, 258

Alpha-ketoglutaramate, 225 Altered state of consciousness

acutely, 6–7, 8t

from basilar migraine, 168 chronic, 7–9, 8t descriptive terms for, 8t

lateral displacement of the diencephalon and, 100 structural lesions associated with, 29–34 subacute, 7–9

Amphetamine, 242t

Amyloid angiopathy, 139–140, 146 ‘‘Amytal interview,’’ 298, 307–308, 327 Anemia, 325

Anemic hypoxia, 211 Anesthesia

barbiturate, 205–206, 323 description of, 205–206

malignant hyperthermia associated with, 262 profound, brain death diagnosis in, 338

Aneurysms bleeding by, 129 mycotic, 140 saccular, 129

vertebrobasilar, 145, 145t Angiogenesis, 94–95 Angiography

computed tomography, 78 magnetic resonance, 79, 336

Anion gap, 240 Anoxemia, 201 Anoxia, 204, 212

Anoxic-ischemic brain damage description of, 206

focal ischemia, 207–208 global ischemia, 206–207 hypoxia, 208

Antidepressants, 241, 245–246 Antidotes

administration of, 315–317 types of, 317t

Antifreeze. See Ethylene glycol Anton’s syndrome, 154 Apathetic thyrotoxicosis, 237 Apnea. See also Sleep apnea

in brain death, 334–335, 335t posthyperventilation, 49, 50f

Apneusis, 50f

Apneustic breathing, 51–52

387