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USMLE Step 2 CK λ Surgery

Simple pneumothorax results from penetrating trauma such as a weapon or the jagged edge of a fractured rib. There is typically moderate shortness of breath with absence of unilateral breath sounds and hyperresonance to percussion. Diagnosis is confirmed with chest x-ray and management consists of chest tubeplacement.

Hemothorax happens the same way but the affected side will be dull to percussion due to blood accumulation in the pleural space. The blood can originate directly from the lung parenchyma or from the chest wall, such as an intercostal artery. Diagnosis is confirmed with chest x-ray. Chest tube placement is necessary to enable evacuation of the accumulated blood to prevent late development of a fibrothorax or empyema, but surgery to stop the bleeding is sometimes required. If the lung is the source of bleeding, it usually stops spontaneously as it is a low pressure system.

In some cases where a systemic vessel such as an intercostal artery is the source of bleeding, thoracotomy is needed to stop the hemorrhage. Indications for thoracotomy include:

Evacuation of >1,500 mL when the chest tube is inserted

Collecting drainage of >1 L of blood over 4 hours, i.e., 250 mL/hr

Severe blunt trauma to the chest may cause obvious injuries such as rib fractures with a flail chest or sucking chest wound, as well as less apparent injuries such as pulmonary contusion, blunt cardiac injury, diaphragmatic injury, and aortic injury.

Sucking chest wounds are obvious from physical exam, as there is a flap that sucks air with inspiration and closes during expiration. Untreated, it will lead to a deadly tension pneumothorax. Initial management is with a partially occlusive dressing secured on 3 sides, with one open side acting as a one-way valve. This allows air to escape but not enter the pleural cavity (to prevent iatrogenic tension pneumothorax and multiple fractures within each rib).

Flail chest occurs with multiple rib fractures that allow a segment of the chest wall to cave in during inspiration and bulge out during expiration (paradoxical breathing). The real problem is the underlying pulmonary contusion. Contused lung is very sensitive to fluid overload, thus treatment includes fluid restriction and pain management. Pulmonary dysfunction may develop, thus serial chest x-rays and arterial blood gases have to be monitored.

Pulmonary contusion can show up right away after chest trauma with “white-out” of the affected lung(s) or can be delayed up to 48 hours. If a respirator is needed, bilateral chest tubes should be considered to prevent a tension pneumothorax from developing as the multiple broken ribs may have punctured the lung. Significant force is necessary to result in a flail chest, so traumatic dissection or transection of the aorta should be evaluated for using a CT angiogram. Finally, ARDS may develop in this scenario.

Blunt cardiac injury should be suspected with the presence of sternal fractures. ECG monitoring will detect any abnormalities. Although serum troponin level was historically obtained, elevations do not generally change management and are therefore not indicated, as treatment is focused on the complications of the injury such as arrhythmias.

Traumatic rupture of the diaphragm shows up with bowel in the chest (by physical exam and x-rays), almost always on the left side (the liver protects the right hemidiaphragm). All suspicious cases should be evaluated with laparoscopy. Surgical repair is typically done from the abdomen.

Traumatic rupture of the aorta is the ultimate “hidden injury.” It most commonly occurs at the junction of the arch and the descending aorta where the relatively mobile aorta is tethered

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Chapter 1 λ Trauma

by the ligamentum arteriosum. Such an injury requires a significant deceleration injury and is totally asymptomatic until the hematoma contained by the adventitia ruptures resulting in rapid death. Suspicion should be triggered by one of the following:

Mechanism of injury

Widened mediastinum on chest x-ray

Presence of atypical fractures such as the first rib, scapula, or sternum, which requires great force to fracture

Diagnosis is made with CT angiogram. Surgical repair is indicated once the patient has been stabilized and more immediate live-threatening injuries have been managed. This can be done in an open or endovascular fashion.

Traumatic rupture of the trachea or major bronchus is suggested by developing subcutaneous emphysema in the upper chest and lower neck, or by a large “air leak” from a chest tube. Chest x-ray and CT scan confirm the presence of air outside the bronchopulmonary tree, and fiberoptic bronchoscopy is necessary to identify the injury and allow intubation past the injury to secure an airway. Surgical repair is indicated

Differential diagnosis of subcutaneous emphysema also includes rupture of the esophagus and tension pneumothorax.

Air embolism should be suspected when sudden death occurs in a chest trauma patient who is intubated and on a respirator. It also can occur when the subclavian vein is opened to the air (e.g. supraclavicular node biopsies, central venous line placement or lines that become disconnected), also leading to sudden cardiovascular collapse and cardiac arrest. Immediate management includes cardiac massage, with the patient positioned in Trendelenburg with the left side down. Prevention includes the Trendelenburg position when the great veins at the base of the neck are to be accessed.

Fat embolism may also produce respiratory distress in a trauma patient who may not have necessarily suffered chest trauma. The typical setting is the following:

Patient with multiple traumatic injuries (including several long bone fractures) develops petechial rashes in the axillae and neck; fever, tachycardia, and low platelet count

At some point patient shows a full-blown picture of respiratory distress, with hypoxemia and bilateral patchy infiltrates on chest x-ray

The mainstay of therapy is respiratory support, and therefore precise diagnosis is not needed and rarely confirmed. Other therapies for this syndrome including heparin, steroids, alcohol, or low-molecular-weight dextran have been discredited.

Abdominal Trauma

For the sake of evaluation and management, abdominal trauma is divided into penetrating and blunt trauma based on the mechanism of injury. Penetrating trauma is further differentiated into gunshot wounds and stab wounds as the pattern of injury based on mechanism is quite different.

Gunshot wounds to the abdomen require exploratory laparotomy for evaluation and possible repair of intra-abdominal injuries, not to “remove the bullet.” Any entrance or exit wound below the level of the nipple line is considered to involve the abdomen.

Stab wounds allow a more individualized approach. If it is clear that penetration has occurred, e.g. protruding viscera, exploratory laparotomy is mandatory.

The same is true if hemodynamic instability or signs of peritoneal irritation develop.

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USMLE Step 2 CK λ Surgery

In the absence of the above, local wound exploration may be performed in the ED to assess whether or not the anterior rectus fascia has been penetrated.

If the fascia is not violated, the intra-abdominal cavity likely has not been penetrated and no further intervention is necessary.

If the fascia has been violated, surgical exploration is indicated to evaluate for bowel or vascular injury, even in the setting of hemodynamic stability and lack of peritoneal findings on physical examination. If there is any question, perform CT.

Blunt trauma to the abdomen with obvious signs of internal injury requires emergent surgical evaluation via exploratory laparotomy. Signs of internal injury include abdominal distention and significant abdominal pain with guarding or rigidity on physical examination consistent with peritonitis. The occurrence of blunt trauma even without obvious signs of internal injury requires further evaluation because internal hemorrhage or bowel injury can be slow and therefore present in a delayed fashion.

Signs of internal bleeding include a drop in BP, a fast and/or thready pulse, a low CVP, and low urinary output. Patients tend to be cold, pale, anxious, shivering, thirsty, and perspiring profusely. These signs of shock occur when 25–30% of blood volume is acutely lost, ~1,500 ml in the average-size adult. There are few places in the body that this volume of blood can be lost without being obvious on physical or radiographic exam.

The head is too small without causing a lethal degree of intracranial pressure.

The neck could contain a significant amount of blood, but such a hematoma would be obvious on physical exam.

The pericardial sac cannot contain the significant an amount of blood loss without resulting in pericardial tamponade and rapid clinical deterioration.

The pleural cavities could easily accommodate several liters of blood, with relatively few local symptoms, but that significant a hemothorax would be obvious on chest x-ray, which is routinely performed in the secondary survey of a trauma patient.

The arms and legs would also be obviously deformed by a large hematoma if present.

That leaves the abdomen, retroperitoneum, thighs (secondary to a femur fracture), and pelvis as the only places where a volume of blood significant enough to cause shock could “hide” in a blunt trauma patient that has become unstable. The femurs and pelvis are always checked for fractures in the initial survey of the trauma patient by physical exam and pelvic x-ray. So a patient who has experienced blunt trauma who has become hemodynamically unstable with normal chest and pelvic x-rays likely has intra-abdominal bleeding.

Diagnosis can be quickly utilizing the “FAST” exam: Focused Abdominal Sonography for Trauma. Bedside U/S evaluates the perihepatic space, perisplenic space, pelvis, and pericardium for free fluid. Fluid is not typically present in these locations, therefore in combination with a clinical suspicion such as hypotension following blunt trauma, should trigger the consideration of an internal injury.

An unstable patient with these findings should be taken to the OR for immediate surgical exploration.

A stable patient in whom the diagnosis is less definite should be taken for a more definitive study, i.e., CT scan. CT will show the presence of intra-abdominal fluid and can accurately delineate the source, typically the liver or spleen.

Additionally, grading scores exist for the extent of injury to these solid organs, with specific guidelines as to when a surgical intervention is indicated versus observation. The details of

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Chapter 1 λ Trauma

these guidelines are outside the scope of the exam. Generally speaking, a patient with intraabdominal bleeding injury from the liver or spleen can be observed as long as they are hemodynamically stable or respond to fluid and blood product administration; the moment instability is mentioned in a vignette, surgical exploration is indicated.

If surgical exploration is indicated for penetrating or blunt trauma, certain principles must be employed.

Prolonged surgical time and ongoing bleeding can lead to the “triad of death”: hypothermia, coagulopathy, and acidosis. The longer a patient is open, these component worsen and precipitate each other, resulting in a vicious cycle ultimately leading to death. Accordingly, the “damage control” approach has been adopted: immediate life-threatening injuries are addressed, less urgent injuries are temporized. Obviously repair of a major vascular structure with ongoing bleeding takes precedence.

––Next comes control of contamination from injury to the GI tract. If a bowel resection is necessary, reconstruction can be delayed as only the contamination is lifethreatening, not the inability to digest food.

––If hypothermia, coagulopathy, or acidosis is setting in and injuries have been controlled, the operation is terminated and the abdomen is packed with gauze pads and closed with a temporary closure. The patient is resuscitated in the ICU, and returns to the OR at a later date when warm, not coagulopathic, and not acidotic for definitive reconstruction and abdominal closure.

If coagulopathy does develop during surgical exploration, it is objectively treated with transfusion of RBCs, fresh frozen plasma, and platelets in equal quantities (1:1:1 ratio). This most realistically mimics the replacement of whole blood and enable not only adequate quantities of hemoglobin, but adequate clotting factors to reverse the developing coagulopathy and enable control of hemorrhage.

The abdominal compartment syndrome is when the pressure in the peritoneal cavity is elevated and leads to end-organ injury. This occurs when a significant amount of fluid is administered in an effort to resuscitate a patient in hypovolemic shock. Bowel edema develops, increasing intra-abdominal pressure, which is detrimental for several reasons.

––First, the elevated pressure leads to decreased perfusion pressure to the viscera, contributing to acute kidney injury and possibly bowel and hepatic ischemia.

––Second, the upward pressure of the viscera on the diaphragm prevents adequate expansion of the lungs and ventilation, contributing to respiratory failure.

––Therefore, if bowel edema is observed or intra-abdominal pressure is elevated following surgical exploration, the abdomen is not closed, rather left open as described in the damage-control approach.

––Similarly, if a patient is not surgically explored but undergoes a significant volume resuscitation and abdominal compartment syndrome develops, a decompressive laparotomy may be indicated. Incidentally, this can occur in non-trauma scenarios requiring massive fluid resuscitation, most notable severe pancreatitis.

A ruptured spleen is the most common source of significant intra-abdominal bleeding in blunt abdominal trauma. Often there are additional diagnostic hints, such as fractures of lower ribs on the left side. Given the limited function of the spleen in the adult, a splenic injury resulting in hemodynamic instability or requiring significant blood product transfusion is an indication for splenectomy. Post-operative immunization against encapsulated bacteria is mandatory (Pneumococcus, Haemophilus influenza B, and meningococcus). However, lesser injuries to the spleen which can be repaired easily are attempted.

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USMLE Step 2 CK λ Surgery

Copyright 2007 Bates, M.D. - Custom Medical Stock Photo. All rights reserved.

Figure I-1-2. CT Scan of Abdomen in 21-Year-Old Man demonstrating Ruptured Spleen and Hemoperitoneum

Pelvic Fracture

The pelvis is a complex ring, much like a pretzel, in that it cannot be fractured in only one location; multiple fractures are typically present. These can range from minor to life-threat- ening. Minor fractures with small pelvic hematomas incidentally identified on CT scan are typically monitored.

In pelvic fracture with ongoing significant bleeding causing hemodynamic instability, management is complex.

The first step for an obvious pelvic fracture in an unstable patient is external pelvic wrapping for stabilization of the pelvis, which limits the potential space for ongoing blood loss.

The next step is not surgical exploration but rather angiography.

––This is because it is incredibly difficult (often impossible) to identify the source of bleeding in the pelvis where a deep cavity contains significant organs and vessels including the complex sacral venous plexus.

––However, interventional radiologists can angiographically identify an arterial source of bleeding and potentially embolize the branch vessels and control hemorrhage.

––If no arterial bleeding is identified, the ongoing blood loss is presumed to be venous in origin, and the internal iliac arteries are prophylactically embolized to prevent the inflow to these bleeding veins.

In any pelvic fracture, associated injuries have to be ruled out. These include rectum (do a rectal exam and rigid proctoscopy), vagina in women (do a pelvic exam); urethra in men (do a retrograde urethrogram), and bladder (addressed in the next section)

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Chapter 1 λ Trauma

Urologic Injury

The hallmark of urologic injury is blood in the urine of someone who has sustained penetrating or blunt abdominal trauma. Gross hematuria in that setting must be investigated with appropriate studies.

Penetrating urologic injuries as a rule are surgically explored and repaired.

Blunt urologic injuries may affect the kidney, in which case the associated injuries tend to be lower rib fractures. If they affect the bladder or urethra, the usual associated injury is pelvic fracture.

Urethral injuries occur almost exclusively in men, is typically associated with a pelvic fracture, and may present with blood at the meatus.

––Other clinical findings include a scrotal hematoma, the sensation of wanting to void but inability to do so, and a “high-riding” prostate on rectal exam (i.e., it is not palpable on rectal exam).

––The key issue in any of these is that a Foley catheter should not be inserted, as it might compound an existing injury, but a retrograde urethrogram should be performed instead.

ººIf Foley catheter placement has been attempted and resistance met, this should be a clue that a urethral injury may be present and attempt should be aborted.

Bladder injuries can occur in either sex, are usually associated with pelvic fracture, and are diagnosed by retrograde cystogram or CT cystography.

––The x-ray study must include post-void films to enable visualization of an extraperitoneal leak at the base of the bladder that might be obscured by a bladder full of dye. Management is surgical repair with protection by a decompressive suprapubic cystostomy or indwelling Foley catheter.

Renal injuries secondary to blunt trauma are usually associated with lower rib fractures. They are assessed by CT and most of the time can be managed without surgical intervention.

––A rare but fascinating potential sequela of injuries affecting the renal pedicle is the development of an arteriovenous fistula leading to CHF. Should renal artery stenosis develop after trauma, renovascular hypertension is another potential sequela.

Scrotal hematomas can attain alarming size, but typically do not need specific intervention unless the testicle is ruptured. The latter can be assessed with sonogram.

Fracture of the penis (fracture of the corpora cavernosa, fracture of the tunica albuginea) occurs to an erect penis, typically as an accident during vigorous intercourse

(with woman on top). There is sudden pain and development of a large penile shaft hematoma, with a normal appearing glans.

––Frequently, the true history will be concealed by an embarrassed patient who concocts a cover story. Emergency surgical repair is required. If not done, impotence will ensue as either arteriovenous shunts or painful erections.

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