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See Fcm.inv.diff.mom in [IBSI Features].​

Page 1316​

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Code Value​

Code Meaning​

Definition​

Notes​

126039​

LesiontoBackgroundSUVRatio​The ratio of the SUV within a tumor to the SUV of a​

 

 

 

pre-defined background region.​

 

 

 

AmoregeneralconceptthanTumortoBackgroundRatio​

 

 

(TBR).​

 

126040​ Background for Lesion to​

The SUV of a pre-defined background region used to​

 

 

Background SUV Ratio​

compute Lesion to Background SUV Ratio.​

 

126050​

Fractal Dimension​

A statistical index of complexity comparing how detail in​

 

 

a fractal pattern changes with the scale at which it is​

 

 

 

measured; a ratio of the change in detail to the change​

 

 

in scale.​

 

126051​

Skewness​

Measure of the asymmetry of the probability distribution​

 

 

of a real-valued random variable about its mean.​

 

126052​

Kurtosis​

Measureofthepeakednessoftheprobabilitydistribution​

 

 

of a real-valued random variable.​

 

126060​ Joint Entropy of GLCM​

The zero order entropy of a Gray Level Co-occurrence​Retired.​

 

 

Matrix(GLCM).Ameasureofdisorder.AbbreviatedENT.​

 

 

 

Replaced by (TU9B, IBSI,​

 

 

See Fcm.joint.entr in [IBSI Features].​

"Joint Entropy of GLCM").​

126061​ Root Angular Second Moment​The square root of the Angular Second Moment (ASM)​Sometimes referred to as​

 

of GLCM​

of a Gray Level Co-occurrence Matrix (GLCM). A​

"energy", "uniformity" or​

 

 

measure of orderliness.​

"uniformityofenergy"butthen​

 

 

 

potentially confused with​

 

 

See http://www.fp.ucalgary.ca/mhallbey/equations.htm.​ASM. Not defined in [IBSI​

 

 

 

Features]​

126062​ Inverse Difference Moment of​ TheInverseDifferenceMoment(homogeneity)ofaGray​Other concepts are​ GLCM​ Level Co-occurrence Matrix (GLCM). Abbreviated IDM.​sometimes referred to as​

"homogeneity", e.g., the​ "inverse difference", which is​ calculated from the absolute​ value of differences rather​ than square of them.​

 

 

 

Retired.​

 

 

 

Replaced by (WF0Z, IBSI,​

 

 

 

"Inverse Difference Moment​

 

 

 

of GLCM").​

126063​

Contrast of GLCM​

The sum of squares of a Gray Level Co-occurrence​

Distinct from "joint (sum of​

 

 

Matrix (GLCM). A measure of gray level variations.​

squares) variance" and​

 

 

Abbreviated CON.​

"dissimilarity".​

 

 

See Fcm.contrast in [IBSI Features].​

Retired.​

 

 

 

Replaced by (ACUI, IBSI,​

 

 

 

"Contrast of GLCM").​

126064​

Dissimilarity of GLCM​

The dissimilarity of a Gray Level Co-occurrence Matrix​Distinctfrom"contrast",which​

 

 

(GLCM). Abbreviated DIS.​

uses square rather than​

 

 

 

absolute value of difference.​

See Fcm.dissimilarity in [IBSI Features].​

Retired.​

Replaced by (8S9J, IBSI,​ "Dissimilarity of GLCM").​

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Page 1317​

Code Value​

Code Meaning​

Definition​

Notes​

126065​ Angular Second Moment of​

The Angular Second Moment of a Gray Level​

Sometimes referred to as​

 

GLCM​

Co-occurrence Matrix (GLCM). Abbreviated ASM.​

"energy", "uniformity" or​

 

 

See Fcm.energy in [IBSI Features].​

"uniformityofenergy"butthen​

 

 

potentially confused with​

 

 

 

square root of ASM.​

 

 

 

Retired.​

 

 

 

Replaced by (8ZQL, IBSI,​

 

 

 

"Angular Second Moment of​

 

 

 

GLCM").​

126066​

Correlation of GLCM​

A measure of the linear dependency of gray levels on​ Correlation is NaN for a​

 

 

those of neighbouring pixels of a Gray Level​

constant image.​

 

 

Co-occurrence Matrix (GLCM). Abbreviated COR.​

Retired.​

 

 

See Fcm.corr in [IBSI Features].​

 

 

Replaced by (NI2N, IBSI,​

 

 

 

 

 

 

"Correlation of GLCM").​

126067​

Gray Level Co-occurrence​

A tabulation of how often different combinations of pixel​

 

Matrix​

values (gray levels) occur in an image. Abbreviated​

 

 

 

GLCM.​

 

 

 

See [IBSI Features].​

 

126070​ Subject Time Point Identifier​

Anidentifierofaspecifictimepointinacontinuum,which​

 

 

is unique within an appropriate local context (such as an​

 

 

entireorganization,systemortreatmentprotocol),which​

 

 

identifies the time point for a specific patient.​

 

126071​ Protocol Time Point Identifier​

Anidentifierofaspecifictimepointinacontinuum,which​

 

 

is unique within an appropriate local context (such as an​

 

 

entireorganization,systemortreatmentprotocol),which​

 

 

identifies the time point "slot" within a treatment protocol​

 

 

using the same value for all patients in the protocol.​

 

126072​

Time Point Type​

Apre-definedtypeofaspecifictimepointinacontinuum.​

126073​

Time Point Order​

A number indicating the order of a time point relative to​

 

 

other time points in the same continuum.​

 

126074​

Posttreatment​

The time after the treatment of interest.​

 

126075​

Eligibility​

For the purpose of determining eligibility for a protocol.​Similar but not identical to​

 

 

 

(21954-3, LN, "Protocol​

 

 

 

eligibility status Cancer"),​

 

 

 

since not constrained to​

 

 

 

cancer, etc.​

126080​

RECIST 1.0​

Response Evaluation Criteria in Solid Tumors version​ More specific than (112022,​

 

 

1.0. See [RECIST] in Normative References.​

DCM, "RECIST") or​

 

 

 

(C1709926, UMLS,​

 

 

 

"RECIST") or (C49164, NCIt,​

 

 

 

"RECIST") in that a specific​

 

 

 

version is specified.​

126081​

RECIST 1.1​

Response Evaluation Criteria in Solid Tumors Version​More specific than (112022,​

 

 

1.1. See Eisenhauer et al. "New Response Evaluation​DCM, "RECIST") or​

 

 

Criteria in Solid Tumours: Revised RECIST Guideline​ (C1709926, UMLS,​

 

 

(version 1.1)." European Journal of Cancer 45, no. 2​

"RECIST") or (C49164, NCIt,​

 

 

(n.d.): 228-47. doi:10.1016/j.ejca.2008.10.026.​

"RECIST") in that a specific​

 

 

 

version is specified.​

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Page 1318​

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Code Value​

Code Meaning​

Definition​

Notes​

126100​ Real World Value Map used for​A reference to the Real World Value Map applied to the​

 

 

measurement​

stored image pixel values before their use for a​

 

 

 

measurement​

 

126200​

Image Library Group​

Acontainerthatgroupscommoninformationaboutaset​

 

 

 

of images used as evidence to produce a report.​

 

126201​

Acquisition Date​

The date the acquisition of data started​

 

126202​

Acquisition Time​

The time the acquisition of data started​

 

126203​

PET Radionuclide Incubation​

The time between the start of injection of the PET​

 

 

Time​

radionuclide and the start of acquisition of the PET data.​

 

126220​

R2-Coefficient​

Coefficient of determination, R2. An indication of​

 

 

 

goodness of fit.​

 

126221​

Chi-square​

Pearson's Χ2 test.​

 

126222​

D-W​

Durbin-Watson statistic for detecting serial correlation in​

 

 

 

residuals.​

 

 

 

See http://en.wikipedia.org/wiki/​

 

 

 

Durbin%E2%80%93Watson_statistic.​

 

126223​

AIC​

Akaike information criterion. A measure of the balance​

 

 

 

betweengoodnessoffitandnumberoffreeparameters.​

 

 

 

See Akaike H. A new look at the statistical model​

 

 

 

identification. IEEE Transactions on Automatic Control.​

 

 

 

1974 Dec;19(6):716-23. http://dx.doi.org/10.1109/​

 

 

 

TAC.1974.1100705.​

 

126224​

BIC​

Bayesianinformationcriterion.Ameasureofthebalance​

 

 

 

between goodness of fit and model complexity.​

 

 

 

See http://en.wikipedia.org/wiki/​

 

 

 

Bayesian_information_criterion.​

 

126300​ Perfusion analysis by Stable​

Perfusion analysis by Stable Xenon CT technique​

 

 

Xenon CT technique​

 

 

126301​ Perfusion analysis by IV​

PerfusionanalysisbyIVIodinatedContrastCTtechnique​

 

 

IodinatedContrastCTtechnique​

 

126302​ Perfusion analysis by Arterial​

Perfusion analysis by Arterial Spin Labeling (ASL) MR​

 

 

Spin Labeling MR technique​

technique​

 

126303​

Perfusion analysis by​

Perfusion analysis by Susceptibility (T2*) MR technique​

 

 

Susceptibility MR technique​

 

 

126310​ Least Mean Square (LMS)​

Least Mean Square (LMS) deconvolution​

 

 

deconvolution​

 

 

126311​ Singular Value Decomposition​Singular Value Decomposition (SVD) deconvolution​

 

 

(SVD) deconvolution​

 

 

126312​

Ktrans​

Ktrans, the volume transfer constant of a tracer diffusion​

 

 

 

kinetic model, specifically the volume transfer constant​

 

 

 

between blood plasma and extravascular extracellular​

 

 

 

space (EES)​

 

See Tofts et al, "Estimating Kinetic Parameters From​ Dynamic Contrast-Enhanced T1-Weighted MRI of a​ DiffusableTracer:StandardizedQuantitiesandSymbols",​ Journal of Magnetic Resonance Imaging, vol. 10, pp.​ 223-232, 1999.​

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Page 1319​

Code Value​

Code Meaning​

Definition​

Notes​

126313​ kep​

 

kep,therateconstantbetweenextravascularextracellular​

 

 

 

space (EES) and blood plasma​

 

 

 

See Tofts et al, "Estimating Kinetic Parameters From​

 

 

Dynamic Contrast-Enhanced T1-Weighted MRI of a​

 

 

DiffusableTracer:StandardizedQuantitiesandSymbols",​

 

 

Journal of Magnetic Resonance Imaging, vol. 10, pp.​

 

 

223-232, 1999.​

126314​

ve​

ve, the fractional (not absolute) volume of extravascular​

 

 

extracellular space (EES) per unit volume of tissue​

 

 

See Tofts et al, "Estimating Kinetic Parameters From​

 

 

Dynamic Contrast-Enhanced T1-Weighted MRI of a​

 

 

DiffusableTracer:StandardizedQuantitiesandSymbols",​

 

 

Journal of Magnetic Resonance Imaging, vol. 10, pp.​

 

 

223-232, 1999.​

126320​

IAUC​

The initial area under the contrast agent​

 

 

concentration-time curve​

126321​

IAUC60​

The initial area under the contrast agent​

 

 

concentration-time curve at 60 seconds after the onset​

 

 

time​

126322​

IAUC90​

The initial area under the contrast agent​

 

 

concentration-time curve at 90 seconds after the onset​

 

 

time​

126323​

IAUC180​

The initial area under the contrast agent​

 

 

concentration-time curve at 180 seconds after the onset​

 

 

time​

126324​

IAUCBN​

The initial area under the contrast agent​

 

 

concentration-time curve, normalized with the​

 

 

corresponding arterial input function, such that IAUCBN​

 

 

= IAUC / IAUCAIF.​

126325​

IAUCBN60​

The initial area under the contrast agent​

 

 

concentration-time curve at 60 seconds after the onset​

 

 

time, normalized with the corresponding arterial input​

 

 

function, such that IAUC60BN = IAUC60 / IAUC60AIF.​

126326​

IAUCBN90​

The initial area under the contrast agent​

 

 

concentration-time curve at 90 seconds after the onset​

 

 

time, normalized with the corresponding arterial input​

 

 

function, such that IAUC90BN = IAUC90 / IAUC90AIF.​

126327​

AUCBN180​

The initial area under the contrast agent​

 

 

concentration-time curve at 180 seconds after the onset​

 

 

time, normalized with the corresponding arterial input​

 

 

function,suchthatIAUC180BN =IAUC180/IAUC180AIF.​

126330​

tau_m​

τm. The mean intracellular water lifetime (τi). Used in the​

 

 

Shutter-Speed Model (SSM) of tracer kinetics.​

126331​

vp​

vp. The fractional (not absolute) blood plasma volume​

 

 

per unit volume of tissue.​

See Tofts et al, "Estimating Kinetic Parameters From​ Dynamic Contrast-Enhanced T1-Weighted MRI of a​ DiffusableTracer:StandardizedQuantitiesandSymbols",​ Journal of Magnetic Resonance Imaging, vol. 10, pp.​ 223-232, 1999.​

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Page 1320​

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Code Value​

Code Meaning​

Definition​

Notes​

126340​

Standard Tofts Model​

A tracer diffusion kinetic model in which the permeability​

 

 

 

is assumed to be isodirectional.​

 

 

See P. Tofts, "Modeling tracer kinetics in dynamic​

 

Gd-DTPAMRimaging",JournalofMagneticResonance​

 

Imaging, vol. 7, pp. 91-101, 1997.​

 

MathematicallyequivalenttothemodelproposedbyKety​

 

in a non-MRI context, hence sometimes refered to as​

 

theTofts-Kety(TK)model.SeeKetySS.TheTheoryand​

 

Applications of the Exchange of Inert Gas at the Lungs​

 

and Tissues. Pharmacological Reviews. 1951 Mar​

 

1;3(1):1-41.​

126341​ Extended Tofts Model​

A tracer diffusion kinetic model in which the permeability​

 

is not assumed to be isodirectional, and which includes​

 

the contribution of tracer in the blood plasma to the total​

 

tissue concentration.​

See P. Tofts, "Modeling tracer kinetics in dynamic​

Gd-DTPAMRimaging",JournalofMagneticResonance​

Imaging, vol. 7, pp. 91-101, 1997.​

126342​ Model-free concentration-time​Asemiquantitativeanalysisofthecontrast-enhancement​ quantitification​ concentration versus time curve that avoids the use of​ a pharmacokinetic model. E.g., integration to compute​

the initial area under the curve.​

126343​ First Pass Leakage Profile​

A tracer diffusion kinetic model that accounts for the​

(FPLP) Model​

tumor leakage profile during the first pass of contrast.​

SeeLi,Ka-Loh,XiaoPingZhu,JohnWaterton,andAlan​ Jackson. "Improved 3D Quantitative Mapping of Blood​ Volume and Endothelial Permeability in Brain Tumors."​ JournalofMagneticResonanceImaging12,no.2(2000):​ 347-357. doi:10.1002/1522-2586(200008)12:​ 2<347::AID-JMRI19>3.0.CO;2-7.​

126344​ Shutter-Speed Model (SSM)​ A tracer diffusion kinetic model that does not assume​ that intercompartmental water molecule exchange is​ infinitely fast.​

See Li, Xin, Wei Huang, Thomas E. Yankeelov, Alina​ Tudorica, William D. Rooney, and Charles S. Springer.​ "Shutter-Speed Analysis of Contrast Reagent​ Bolus-TrackingData:PreliminaryObservationsinBenign​ and Malignant Breast Disease." Magnetic Resonance in​ Medicine 53, no. 3 (2005): 724-29.​ doi:10.1002/mrm.20405.​

126345​ Gamma Capillary Transit Time​Atracerdiffusionkineticmodelthatmathematicallyunifies​

(GCCT) Model​ theTofts,ExtendedTofts,AdiabaticTissueHomogeneity,​

and Two Compartment Exchange models​

See Schabel MC. A unified impulse response model for​ DCE-MRI. Magnetic Resonance in Medicine.​ 2012;68(5):1632-46. doi:10.1002/mrm.24162.​

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