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Note
Since the Adult Mouse Anatomy Ontology is not in the UMLS, the mapping of Mouse Anatomy codes described here is an extract of a mapping to the NCI Thesaurus described in Hayamizu TF, de Coronado S, Fragoso G, Sioutos N, Kadin JA, Ringwald M. The mouse-human anatomy ontology mapping project. Database: The Journal of Biological Databases and Curation 2012;2012:bar066. doi:10.1093/database/bar066. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308156/. The mapping files used can be found at ftp://ftp.informatics.jax.org/pub/reports/ma2ncit.obo.
The NCI Thesaurus codes were then used to look up corresponding concepts in UMLS, from which SNOMED and FMA codes were extracted automatically (and various conflicts and ambiguities resolved manually). The same correspondence to existing Body Part Examined values is used as in other tables in this Annex.
Another mapping project using the FMA as a reference ontology was not used, since the files were not available. See Zhang S, Bodenreider O. Alignment of Multiple Ontologies of Anatomy: Deriving Indirect Mappings from Direct Mappings to a Ref- erence.AMIAAnnualSymposiumProceedings2005;2005:864-868http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560629/.
Table L-4. Correspondence between Animal-specific and Generic NCI Thesaurus Codes
Code Meaning |
Generic NCIt ID |
Generic UMLS |
Mouse-specificMouse-specificRat-specificRat-specific |
|
|
Concept UniqueID |
NCIt ID |
UMLS Concept |
NCIt ID |
UMLS |
|
|
|
|
UniqueID |
|
Concept |
|
|
|
|
|
|
UniqueID |
Adrenal gland |
C12666 |
C0001625 |
C22635 |
C1515888 |
C60540 |
C1882555 |
Ankle joint |
C32078 |
C0003087 |
|
|
|
|
Aorta |
C12669 |
C0003483 |
C23600 |
|
C60541 |
C1882561 |
Bladder |
C12414 |
C0005682 |
C22729 |
C1511191 |
C60634 |
C1882899 |
Brain |
C12439 |
C0006104 |
C22606 |
C1521713 |
C60544 |
C1882598 |
Breast |
C12367 |
C0929301 |
C22549 |
C1512980 |
C60585 |
C1882771 |
Bronchus |
C12683 |
C0006255 |
C24050 |
C1518036 |
C60546 |
C1882603 |
Buccalregionofface |
C13070 |
C0007966 |
C23972 |
|
|
|
Calcaneus |
C32250 |
C0006655 |
|
|
|
|
Carotid Artery |
C12687 |
C0007272 |
C23618 |
|
|
|
Cerebellum |
C12445 |
C0007765 |
C22609 |
C1522278 |
C60550 |
C1882617 |
Cervix |
C12311 |
C0007874 |
|
|
C60635 |
C1882903 |
Clavicle |
C12695 |
C0008913 |
C23626 |
|
|
|
Coccyx |
C12696 |
C0009194 |
|
|
|
|
Colon |
C12382 |
C0009368 |
C22528 |
C1522281 |
C60554 |
C1882628 |
Cornea |
C12342 |
C0010031 |
C22717 |
C2700413 |
|
|
Coronary artery |
C12843 |
C0205042 |
C23773 |
|
|
|
Digit |
C40186 |
C0582802 |
|
|
|
|
Duodenum |
C12263 |
C0013303 |
C22523 |
C1522711 |
C60558 |
C1882648 |
Elbow joint |
C32497 |
C0013770 |
|
|
|
|
Esophagus |
C12389 |
C0014876 |
C22509 |
C1516967 |
C60563 |
C1882662 |
Extremity |
C12429 |
C0015385 |
C23363 |
|
|
|
Eye |
C12401 |
C0015392 |
C22711 |
C1517081 |
C60565 |
C1882665 |
Eyelid |
C12713 |
C0015426 |
C23644 |
|
C60566 |
C1882666 |
Face |
C13071 |
C0015450 |
C23973 |
|
|
|
Femur |
C12717 |
C0015811 |
C23648 |
|
C60567 |
C1882669 |
Fibula |
C12718 |
C0016068 |
C23649 |
|
|
|
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|
|
Code Meaning |
Generic NCIt ID |
Generic UMLS |
Mouse-specificMouse-specificRat-specificRat-specific |
|
|
Concept UniqueID |
NCIt ID |
UMLS Concept |
NCIt ID |
UMLS |
|
|
|
|
UniqueID |
|
Concept |
|
|
|
|
|
|
UniqueID |
Sternum |
C12793 |
C0038293 |
C23724 |
|
C60622 |
C1882873 |
Temporomandibular |
C32888 |
C0039493 |
|
|
|
|
joint |
|
|
|
|
|
|
Testis |
C12412 |
C0039597 |
C22178 |
C1515315 |
C60625 |
C1882878 |
Thigh |
C33763 |
C0039866 |
|
|
|
|
Thumb |
C52834 |
C0040067 |
|
|
|
|
Thymus |
C12433 |
C0040113 |
C22553 |
C1515438 |
C60627 |
C1882880 |
Thyroid |
C12400 |
C0040132 |
C22650 |
C1522142 |
C60628 |
C1882881 |
Tibia |
C12800 |
C0040184 |
C23731 |
|
|
|
Toe |
C33788 |
C0040357 |
|
|
|
|
Tongue |
C12422 |
C0040408 |
C22508 |
C1519545 |
C60629 |
C1882882 |
Ulna |
C12809 |
C0041600 |
C23740 |
|
|
|
Upper arm |
C32141 |
C0446516 |
|
|
|
|
Ureter |
C12416 |
C0041951 |
C22738 |
C1519822 |
C60632 |
C1882897 |
Urethra |
C12417 |
C0041967 |
C22739 |
C1519824 |
C60633 |
C1882898 |
Uterus |
C12405 |
C0042149 |
C22671 |
C1519876 |
C60636 |
C1882904 |
Vagina |
C12407 |
C0042232 |
C22676 |
C1519910 |
C60637 |
C1882906 |
Vulva |
C12408 |
C0042993 |
C22677 |
C1520067 |
|
|
Note
For the mouse, NCIt contains some duplicate anatomical concepts, including those which have been marked inactive and appear to have been replaced with improved codes for the "Mouse Models of Human Cancers Consortium" (MMHCC). Whenever duplicates were found, the MMHCC concept has been used in this table.
This table was produced by searching NCIt for all concepts that had "mouse" or "rat" in their concept name or synonyms, and then using that synonym with the word "mouse" or "rat" removed, to match against generic concept names.
The NCI Thesaurus codes were then used to look up corresponding concepts in UMLS, though not all of the concepts are included in UMLS yet (especially the MMHCC concepts).
Table L-5. Pairedness of Anatomic Concepts
SNOMED Code Value |
Code Meaning |
Paired Structure |
77012006 |
Amniotic fluid |
N |
113345001 |
Abdomen |
N |
416949008 |
Abdomen and Pelvis |
N |
7832008 |
Abdominal aorta |
N |
85856004 |
Acromioclavicular joint |
Y |
23451007 |
Adrenal gland |
Y |
70258002 |
Ankle joint |
Y |
128585006 |
Anomalous pulmonary vein |
N |
128553008 |
Antecubital vein |
Y |
194996006 |
Anterior cardiac vein |
N |